Fri Apr 11 2025

138 articles - From Friday Apr 04 2025 to Friday Apr 11 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Am J Gastroenterol

Routine Polypectomy Practices Vary Widely Among US Endoscopists and Commonly Deviate from Guidelines: An Analysis of Colonoscopy Registry Data.

Polypectomy technique varies widely among US endoscopists and may not follow best practices.

Pubmed   Journal   ReadQx 

THE SAN DIEGO CONSENSUS FOR LARYNGOPHARYNGEAL SYMPTOMS AND LARYNGOPHARYNGEAL REFLUX DISEASE.

The San Diego Consensus represents the formal modern-day inter-disciplinary care paradigm to evaluate and manage LPS and LPRD.

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Endoscopy

Curriculum for training in peroral endoscopic myotomy (POEM) in Europe (Part I): European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

7: POEM competence should reflect the technical success rate, both the short- and long-term clinical success rates, and the rate of true adverse events. 8: A POEM center should maintain a prospective registry of al procedures performed, including patient work-up and outcomes, procedural techniques, and adverse events.

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J Hepatol

Deceased donor liver utilisation and assessment: Consensus guidelines from the European Liver and Intestine Transplant Association.

Online voting was held to approve statements according to a modified Delphi method; statements reaching ≥85% agreement were approved. Statements addressing liver utilisation, the definition of high-risk livers, and strategies and criteria for dynamic liver assessment are presented.

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EASL Clinical Practice Guidelines on TIPS.

The aim of these EASL guidelines is to comprehensively address al aspects of TIPS in patients with cirrhosis. Other related topics, such as the use of TIPS in surgical settings and in vascular liver disorders, are covered in separate dedicated clinical practice guidelines.

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J Neurogastroenterol Motil

2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome.

The modified Delphi method was used to achieve expert consensus to adopt the core recommendations of the guidelines. These guidelines serve as a reference for clinicians (including primary care physicians, general healthcare providers, medical students, residents, and other healthcare professionals) and patients, helping them to make informed decisions regarding IBS management.

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Meta-analysis

meta-analyses and systematic reviews

Am J Gastroenterol

Suggestions to Strengthen a Systematic Review.

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Clin Gastroenterol Hepatol

High Global Prevalence of Steatotic Liver Disease and Associated Subtypes: a Meta-Analysis.

Prevalence was notably elevated in individuals with type 2 diabetes (70.2%; 95% CI: 66.1-73.9; I2 = 65.4%) and in overweight/obese populations (70.7%; 95% CI: 43.2-88.4; I2 = 99.0%). The high prevalence of SLD shows that there remains an urgent need for targeted public health interventions and policies to address the modifiable risk factors contributing to the global burden of SLD.

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Gastroenterology

Large Language Model-supported Systematic Reviews to Augment Clinical Guideline Development: An AGA Pilot.

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J Neurogastroenterol Motil

Association of Proton Pump Inhibitor Use With Gastric Cancer in Regions With High Prevalence of Gastric Cancer: Systematic Review and Meta-analysis.

pylori. Optimization of long-term PPI use seems to be necessary in regions where gastric cancer is prevalent.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Biopsy-Sparing Diagnosis of Coeliac Disease Based on Endomysial Antibody Testing and Clinical Risk Assessment.

Low-risk adult patients could have been safely diagnosed with coeliac disease non-invasively based on EmA without endoscopy and duodenal biopsy. Older patients with alarm symptoms should undergo endoscopy with duodenal biopsy to avoid missing non-coeliac enteropathies. Further validation of our results is necessary.

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Clinical Trial: Dose-Finding Study of Linaprazan Glurate, A Novel Potassium-Competitive Acid Blocker, Versus Lansoprazole for the Treatment of Erosive Oesophagitis.

Linaprazan glurate demonstrated high 4-week healing rates compared to lansoprazole, with a good safety profile, supporting its further development.

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Diagnostic Accuracy of an Add-On, Blood-Based Screening Test for Colorectal Cancer in Two Established Screening Programmes.

ClinicalTrials. gov identifier: NCT04980443, NCT05205967, NCT04369053.

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Extracellular Vesicles miRNome Profiling Reveals miRNAs Engagement in Dysfunctional Lipid Metabolism, Chronic Inflammation and Liver Damage in Subjects With Metabolic Dysfunction-Associated Steatotic Liver Disease.

In addition, let-7d-5p and let-7f-5p inversely correlated with the circulating and hepatic expression of pro-inflammatory cytokines, which increased by increasing degrees of AT-IR. Our results suggest an intertwined connection between miR-122-5p, miR-375-3p, and the let-7 family in modulating lipid derangements and inflammatory pathways in patients with 'at-risk MASH', paving the basis for further studies aiming at investigating their potential therapeutic value.

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Immigration Factors and Monitoring of Chronic Hepatitis B Infection Among Foreign-Born: The FOCUS-HBV Multicentre Cohort.

Adherence to long-term monitoring is suboptimal among a diverse cohort of immigrants with chronic HBV. More efforts to engage and retain immigrants in care are needed.

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Longitudinal Relationship Between Elevated Liver Biochemical Tests and Negative Clinical Outcomes in Primary Biliary Cholangitis: A Population-Based Study.

Prolonged elevation of multiple hepatic biomarkers and fibrosis scores is associated with a greater risk of negative clinical outcomes, underscoring the importance of ongoing monitoring beyond the guideline-recommended initial treatment response to guide timely treatment decisions and improve PBC management.

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Real-World Effectiveness and Safety of Mirikizumab Induction Therapy in Patients With Ulcerative Colitis: A Multicentre Retrospective Observational Study.

There were no adverse events leading to permanent discontinuation of mirikizumab or death. This real-world study demonstrated the short-term effectiveness and safety of mirikizumab in patients with UC.

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Risk of De Novo Inflammatory Bowel Disease in Patients With Psoriasis and Psoriatic Arthritis Treated With IL-17A Inhibitors: A Population-Based Study.

Among 13,216 matched patients per group, 142 developed IBD with IL-17 inhibitors versus 60 with apremilast (aHR = 2.50, 95% CI: 1.85-3.39). IL-17 inhibitors increase IBD risk, necessitating careful patient selection and monitoring.

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Therapeutic Sequences of Systemic Therapy After Atezolizumab Plus Bevacizumab for Hepatocellular Carcinoma: Real-World Analysis of the IMMUreal Cohort.

Sequential therapy following atezolizumab and bevacizumab is feasible only for selected patients. However, preserving liver function seems crucial to optimising multi-line therapy and improving outcomes in advanced hepatocellular carcinoma.

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Three-Dimensional Transjugular Intrahepatic Portosystemic Shunt Geometry Predicts Shunt Dysfunction.

This retrospective monocentric study includes patients from the NEPTUN cohort (registered at ClinicalTrials. gov; Identifier: NCT03628807).

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Am J Gastroenterol

A Risk Stratification Tool for Relapse After Intravenous-to-Subcutaneous Switching of Infliximab in Patients with Inflammatory Bowel Diseases.

Pre-switch infliximab clearance and fecal calprotectin are accurate predictors of relapse after switching to subcutaneous infliximab. An interactive risk stratification tool facilitates confirmation of a stratified medicine approach to improve infliximab therapy in IBD.

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Clinical and HLA associations of fluoroquinolone induced liver injury: results from the Drug-Induced Liver Injury Network.

FQ DILI is a class effect that presents with a short latency, variable pattern of liver injury, and carries a significant risk of chronicity and mortality. There is a significant association with HLA-DQA1*03:01 and HLA B*57:01.

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Efficacy of Polysaccharide Hemostatic Powder on blood oozing among patients with Post-Endoscopic Sphincterotomy Bleeding: A Randomized Controlled Trial.

PHP is not inferior to endoscopic clip and could be of use in immediate hemostasis for non-pulsatile post-EST bleeding, with the added advantage of ease of use. Further research is needed to assess its efficacy in preventing delayed bleeding. (chictr.org.cn, ChiCTR2400092280).

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Existential Reflections by Older Adults with Inflammatory Bowel Diseases on Medical and Surgical Treatments.

Supporting older adults with IBD to feel less resigned with their disease is critical. Providers should consider redefining what "feeling normal" means to facilitate disease acceptance and present treatment information with minimal bias.

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Is Carbohydrate Intolerance associated with carbohydrate malabsorption in Disorders of Gut-Brain Interaction (DGBI)?

Carbohydrate intolerance affects a substantial group of DGBI patients, impacting their quality of life and symptom severity. Further research is needed to explore the underlying mechanisms in patients who do not have carbohydrate malabsorption/maldigestion.

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LONG-TERM SUSTAINED IMPROVEMENT IN UNPLANNED HEALTHCARE UTILIZATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE.

Efforts to sustain improvements after a QI initiative can result in long-term improvement in patient outcomes.

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PATIENT REPORTED OUTCOME MEASURES IN BENIGN ESOPHAGEAL DISORDERS.

Future efforts should focus on creating user-friendly PROs that comprehensively evaluate not just clinical presentation but also the disease state, which will enhance clinical symptom follow-up, quality of life assessment and research applications. Assessments of hypervigilance and visceral anxiety will complement these applications as these measures are both a PRO and an important moderator of symptom severity and quality of life.

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The Impact of Cannabis Use in Gastroparesis: A Propensity Matched Analysis 41,374 gastroparesis patients.

Cannabis use in gastroparesis patients appears to increase healthcare utilization. These findings underscore the need to carefully assess the risks and benefits of cannabis in gastroparesis management. Prospective studies are essential to evaluate cannabinoids' efficacy and safety in this context.

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The Utility of Multitarget Stool DNA Testing in Community-Based Clinical Practice.

The rate of colon cancer detection (10/5,827 (0.2%) patients for whom it was ordered and 10/3,119 (0.3%) who completed the test) was lower than expected in a screening cohort. The majority of patients who completed MT-sDNA testing had a false positive result for advanced adenomas or CRC (73%). Together, these findings raise questions about the effectiveness of screening based on MT-sDNA testing in an average risk population.

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Clin Gastroenterol Hepatol

Biologic switch timing and risk of infection in patients with ulcerative colitis/Crohn's disease: a retrospective study.

Overlapping switches were common and not associated with an increased risk of serious infection versus non-overlapping biologics. Shortened washout periods may pose minimal safety risks to patients while improving UC/CD therapy management and improving trial recruitment.

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Effect, tolerability, and safety of exclusive palatable elemental diet in patients with intestinal microbial overgrowth.

PED significantly impacts the gut microbiome. Tolerance to EDs improve with enhanced palatability. Larger studies with longer follow-up are needed to assess response durability. (ClinicalTrials.gov ID NCT05978973).

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Steatotic liver disease classification is dynamic, affecting clinical trial eligibility and subclass-specific treatments.

SLD and the subclassification hereof is highly dynamic, especially driven by changes in alcohol use and hepatic steatosis. This affects eligibility for clinical trials and clinical management of patients with SLD.

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Endoscopy

Assessment of the participation rate and effectiveness of upper gastrointestinal cancer screening in China: a multicenter population-based screening study.

Participation in endoscopic screening among a high-risk UGIC population in China was low. We found that one-time endoscopic screening significantly reduced mortality caused by UGIC.

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Endoscopic balloon dilation with steroid injection versus radial incision and cutting with steroid for refractory esophageal anastomotic stricture: a randomized study.

EBD combined with steroid injection is the standard treatment for refractory anastomotic stricture after esophagectomy.

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Simulators and training models for diagnostic and therapeutic gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review.

In Part I, only mechanical simulators are reported and described. In Part II, animal simulators (ex vivo/in vivo) and virtual reality models are detailed, together with prototypes that are currently not commercially available.

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The Safety and Efficacy of Endoscopic Intraperitoneal Subserosal Dissection for Gastric Submucosal Tumors with Extraluminal Growth Pattern.

EISD appears to be a feasible and safe method for removing gastric extraluminal SMTs in selected patients.

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Gastroenterology

Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): a randomized controlled trial.

Surveillance did not improve overall survival or cancer-specific survival. 'At need' endoscopy may be a safe alternative for low-risk patients.

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FUT7 improves intestinal immune homeostasis in IBD by enhancing Treg intestinal homing and immunosuppression.

FUT7 enhances Treg intestinal homing and immunosuppression. Thus, upregulating FUT7 expression in Tregs could be a novel therapeutic strategy for IBD.

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KRASG12D cells override homeostatic cell elimination mechanisms in adult pancreas via Wnt5a and cell dormancy.

RAS mutant cells activate Wnt5a and cell dormancy to avoid cell expulsion and to survive in the adult pancreas.

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MASH Adipose Tissue Macrophages Secrete Extracellular Vesicles That Activate Liver Fibrosis in Obese Male Mice.

Identification of the fibrogenic miRs, miR-155 and miR-34a, within MASH-ATM-sEVs, highlights the mechanistic importance of extrahepatic signals in MASH. These findings show the therapeutic potential of modulating macrophage phenotypes and their sEV cargo to ameliorate MASH.

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TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental Crohn's disease.

We demonstrate that functional DR3 receptor is essential for Th9 cell pathogenicity, revealing a new mechanism by which TL1A/DR3 signaling drives experimental CD-like ileitis. The TL1A/DR3/Th9 pro-inflammatory pathway may offer a novel therapeutic target for patients with CD.

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Gastrointest Endosc

Comparing the feasibility, safety, and efficacy of Stretta radiofrequency and anti-reflux ablation therapy for treating patients with refractory gastroesophageal reflux disease: A retrospective, single-center cohort study.

Both groups showed similar improvements in GERDQ scores; however, SRF was more effective in terms of PPI withdrawal and caused fewer complications. In contrast, ARAT was better at improving Hill's valve grading and resolving Barrett's esophagus.

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Gut

Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19.

We identified a possible manifestation of an immune-mediated postacute sequel to COVID-19 associated with a characteristic immune infiltrate in children with AHUO. COVID-19 testing should be considered in paediatric AHUO.

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Colorectal cancer incidence after the first surveillance colonoscopy and the need for ongoing surveillance: a retrospective, cohort analysis.

Patients with high-risk findings at both baseline and SC1 needed an SC2, while those with low-risk findings at SC1 did not, regardless of their baseline findings.

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Opposite regulation of intestinal and intrahepatic CD8+ T cells controls alcohol-associated liver disease progression.

ALD is associated with loss of duodenal CD8+ T cells but elevation of intrahepatic CD8+ T cells, which aggravates and ameliorates ALD, respectively. Restoration of survival and functions of intestinal and intrahepatic CD8+ T cells may represent a novel therapeutic strategy for ALD patients.

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Reactive cholangiocyte-derived ORM2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming.

Mechanistically, ORM2 effects were mediated by an inositol 1,4,5-trisphosphate receptor type 2-dependent calcium pathway. This study reveals a paracrine communication circuit during ductular reaction, in which reactive cholangiocyte-derived ORM2 reprogrammes liver macrophages, participating in a pathogenic remodelling of the immune biliary niche.

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Hepatology

Advances in imaging - Elastography.

Spleen stiffness measurement (SSM) complements liver assessments, enhancing the identification of portal hypertension and refining patient risk stratification. This review covers current clinical applications but also anticipates future innovations such as artificial intelligence based algorithms that could expand elastography's clinical impact so improving patient outcomes.

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Cell therapies and liver organogenesis technologies: Promising strategies for end-stage liver disease.

Notably, liver replacement technologies hold considerable potential for producing biologically functional and transplantable liver grafts. In this review, we discuss the fundamental principles and recent advancements in cell therapies and liver organogenesis technologies while also addressing the challenges and future prospects in this rapidly evolving field.

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Portal sinusoidal vascular diseases: Assessment and therapy.

This review discusses methods for assessing PSVD, including clinical and histological features, imaging techniques, and currently available treatments. It also addresses the challenges posed by the new nomenclature and the remaining questions in disease assessment.

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Renin-angiotensin-aldosterone system inhibitor use improves clinical outcomes in patients with metabolic dysfunction-associated steatotic liver diseases: Target trial emulation using real-world data.

ACEi/ARB use in patients with MASLD was associated with a reduced risk of mortality, MALO, and MACE compared to CCB use. A large prospective study is needed for external validation.

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Simulating the impact of survival benefit-based liver transplant organ allocation.

Our simulations predicted that survival benefit-based allocation would only increase post-transplant survival by an average of 18 days per recipient, at the expense of a simulated increase in waitlist mortality of 400 deaths per year. The current practice of liver transplantation, with sickest-first allocation operating in a system where transplant physicians ration organs to maximize outcomes, survival benefit overall is maintained and not compromised.

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Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1.

Analyses of human MASH samples revealed a positive correlation between IRE1 signaling and P4HB/PDIA1 expression as well as the severity of the disease. Altogether, our results establish a role of the IRE1/P4HB axis in the regulation of collagen production and support its implication in the pathogenesis of liver fibrosis.

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J Hepatol

Cisplatin-induced Disruption of Mitochondrial Divisome Leads to Enhanced Cisplatin Resistance in Cholangiocarcinoma.

We proposes a novel feasible treatment strategy to reverse CDDP resistance in CCA through targeting mitochondria morphology. Our study highlights the importance of monitoring dynamic changes at the protein and organelle levels during anticancer treatment, providing robust evidence for functional precision oncology. Impact and implications This study identifies that high INF2 expression at baseline is associated with poor prognosis in cholangiocarcinoma (CCA) patients. Moreover, cisplatin-induced INF2 degradation via proteasomal and SEC62-mediated ER-phagy is revealed as a key driver of mitochondrial hyperfusion and chemoresistance in CCA. It establishes mitochondrial morphology targeting as a novel strategy to overcome chemotherapy resistance. Furthermore, this study emphasizes the need to focus on dynamic changes in tumor proteins or organelle functions during treatment (functional precise oncology), rather than limiting analysis to static tumor states. Given that inhibition of oncogenes may lead to potential resistance mechanisms, comprehensive preclinical evaluations are essential before clinical application.

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J Neurogastroenterol Motil

Association Between Caffeine Intake and Stool Frequency- or Consistency-Defined Constipation: Data From the National Health and Nutrition Examination Survey 2005-2010.

Caffeine consumption is not associated with stool frequency or consistency-defined constipation. Nevertheless, increased caffeine intake may decrease the risk of constipation (defined by stool frequency) among participants in the high-cholesterol intake group.

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Association of Genetically Predicted Obesity and Stool Frequency: Evidence From an Observational and Mendelian Randomization Study.

Obesity-related anthropometric indicators were causally associated with increased stool frequency in the overall and central obesity groups. Weight loss could be a potential approach to improve gastrointestinal regularity in individuals with obesity.

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Gastric Myoelectrical Activity Subtypes in Functional Dyspepsia and Gastroparesis.

WLST-electrogastrography coupled with GE study may distinguish between normal/dysrhythmic GMA revealing pathophysiologicalphenotypes of GP and FD. Analysing extent of power change in normogastric, and dysrhythmic frequencies may comprehensively elucidate disease severity.

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Long-term Prognosis and Prognostic Factors in Ineffective Esophageal Motility.

Patients with ineffective esophageal motility continue to experience long-term esophageal symptoms at follow-up. Provocative tests seem to have the potential to partly predict the long-term prognosis of dysphagia.

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Overlapping Reflux Symptoms in Functional Dyspepsia Are Mostly Unrelated to Gastroesophageal Reflux.

Strikingly, these symptoms primarily diverged from reflux etiology and exhibited suboptimal responses to PPI intervention. These findings challenge prevailing paradigms and accentuate the imperative for nuanced therapeutic approaches tailored to the distinctive characteristics of overlapping reflux symptoms in the context of FD.

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Panenteric Transit Times and Contractile Activity in Diabetic Gastroenteropathy.

Gastrointestinal transit times, as well as antral and colonic contractile activity, differed between individuals with diabetic gastroenteropathy and controls. The overall gastric contraction frequency was associated with symptom severity.

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Validation of the London Classification for Rectal Hyposensitivity in an Anorectal Manometry Database of 2540 Patients With Functional Defecatory Disorder.

Defining RH based on 1 or more abnormal sensory thresholds showed better clinical correlation with patient characteristics. However, further prospective studies are needed to validate these findings before proposing revisions to the current London classification criteria.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Editorial: 'Risk-Adapted Starting Ages of Colorectal Cancer Screening for People With Diabetes or Metabolic Syndrome'.

Pubmed   Journal   ReadQx 

Editorial: How to Interpret Clinical Impact of Viral Replication Activity for Postoperative Recurrence of HBV-Related HCC.

Pubmed   Journal   ReadQx 

Editorial: Obesity and Outcomes on Advanced Therapy in Ulcerative Colitis-The Fat of the Matter.

Pubmed   Journal   ReadQx 

Gastroenterology

Ethical considerations for the use of deception in pediatric research: Reflections on the use of deceptive placebo in children with DGBI.

Pubmed   Journal   ReadQx 

Gastrointest Endosc

A note from the Editor-in-Chief.

Pubmed   Journal   ReadQx 

Cold snare polypectomy: Is it safe for patients on antiplatelet therapy?

Pubmed   Journal   ReadQx 

EUS-guided biliary drainage: old dogs can learn new tricks.

Pubmed   Journal   ReadQx 

EndoZip: Are we ready for robotic systems in obesity?

Pubmed   Journal   ReadQx 

Pearls learned from a decade of experience with peroral endoscopic myotomy.

Pubmed   Journal   ReadQx 

Self-assembling peptide use in colonic diverticular bleeding: Too early to tell?

Pubmed   Journal   ReadQx 

Will predicting a benign esophageal stricture to be at high risk of being refractory at index endoscopy help in management?

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

Globus: Its True Relationship to Acid Reflux? Opposing Patterns of Location-specific Basal Pressure Compared to Gastroesophageal Reflux Disease.

Pubmed   Journal   ReadQx 

Overlap Between Gastroesophageal Reflux Disease and Functional Dyspepsia: Do We Need a New Management Paradigm?

Pubmed   Journal   ReadQx 

Potassium-competitive Acid Blockers for Treatment of Extraesophageal Symptoms and Signs.

Therefore, P-CABs appear to have a treatment role in extraesophageal symptoms and signs of GERD. However, considering that P-CABs are not superior to PPIs, large-scale, multi-center studies with double dose P-CABs over a prolonged period of time may elucidate a subgroup of patients in whom P-CABs are beneficial in ameliorating extraesophageal symptoms and signs.

Pubmed   Journal   ReadQx 

The Duodenal Microenvironment in Functional Dyspepsia.

We discuss the potential triggers for these observed alterations, including psychological comorbidities, luminal alterations and food related triggers. In summary, this review presents the evidence of molecular and cellular changes in patients with FD, with an impaired duodenal barrier and activated mucosal eosinophils and mast cells, challenging the notion that FD is purely functional, and offering different targets for potential future treatments.

Pubmed   Journal   ReadQx 


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol

2025 CME Information.

Pubmed   Journal   ReadQx 

A case of multiple gastrointestinal ulcers caused by dental floss used for endoscopic submucosal dissection defect closure.

Pubmed   Journal   ReadQx 

Accurately Predicting Recurrent Primary Sclerosing Cholangitis After Liver Transplantation.

Pubmed   Journal   ReadQx 

Barrett's Esophagus in Time and Space: A Methylation Panel for Tracking Esophageal Cancer.

Pubmed   Journal   ReadQx 

CENTORING AND ANCHORING APPROACH TO ENDOSCOPICALLY MANAGE NON-HEALING PEG SITE FISTULA.

Pubmed   Journal   ReadQx 

Calendar of Courses, Symposiums and Conferences.

Pubmed   Journal   ReadQx 

Early Stage Crohn's Disease-Associated Small Bowel Adenocarcinoma at Ileal Stenosis Detected by Ballon-Assisted Enteroscopy.

Pubmed   Journal   ReadQx 

Novel Closure of Large Gastric Defect Using a Dual-Channel Endoscope.

Pubmed   Journal   ReadQx 

Rapid Development of Giant Esophageal Pseudo-Diverticulosis.

Pubmed   Journal   ReadQx 

Response to Ling et al.

Pubmed   Journal   ReadQx 

Response to Wei.

Pubmed   Journal   ReadQx 

Treatment of Clostridioides difficile: The Times They are a Changing.

Pubmed   Journal   ReadQx 

Endoscopy

A case of benign biliary stricture treated with a magnetic compression anastomosis technique.

Pubmed   Journal   ReadQx 

A case of collagenous gastritis: endoscopic and endocytoscopic features.

Pubmed   Journal   ReadQx 

A modified detachable snare closure for post-endoscopic submucosal dissection defects: the clip, loop, and clips technique.

Pubmed   Journal   ReadQx 

A rare clinical case of a gastric adenocarcinoma of fundic gland-type associated with a second independent gastric signet-ring cell carcinoma.

Pubmed   Journal   ReadQx 

Endoscopic removal of a large gastric trichobezoar using a snare modified from a lithotripter to facilitate argon plasma coagulation.

Pubmed   Journal   ReadQx   PMC

Endoscopic submucosal dissection of a rectal lesion using a new flower-shaped multiband traction system.

Pubmed   Journal   ReadQx   PMC

Endoscopic ultrasound-guided portal vein sampling and circulating tumor cells: the next frontier in pancreatic cancer, or a step too far?

Pubmed   Journal   ReadQx 

Gel submarine technique: a novel gel immersion endoscopy for securing the view in emergency upper gastrointestinal endoscopy.

Pubmed   Journal   ReadQx 

Lynch-related adenocarcinoma in a cervical gastric inlet patch.

Pubmed   Journal   ReadQx 

Novel endoscopic full-thickness resection device for colon polyp resection.

Pubmed   Journal   ReadQx 

Open-pore drainage film-based vacuum stent for intraluminal endoscopic negative pressure therapy of the esophagus.

Pubmed   Journal   ReadQx 

Successful delayed endoscopic management of dislocated hepaticogastrostomy stent with self-expanding metal stent and esophageal perforation closure.

Pubmed   Journal   ReadQx 

Gastroenterology

A Rare Cause of Abdominal Pain and Melena.

Pubmed   Journal   ReadQx 

A learner's guide to optical diagnosis in endoscopy: training strategies and practical applications.

Pubmed   Journal   ReadQx 

Gastro Curbside Consult: A rare case of ileocolitis.

Pubmed   Journal   ReadQx 

How Will the Future Judge Us?

Pubmed   Journal   ReadQx 

Remodeling the colon with ileal properties to treat short bowel syndrome.

Pubmed   Journal   ReadQx 

Gut

Alcohol exhibits contrasting effects on CD8+ T cells in the gut and liver in alcohol-associated liver disease.

Pubmed   Journal   ReadQx 

Immune pathology in paediatric acute hepatitis of unknown origin - uncovering the link to COVID-19.

Pubmed   Journal   ReadQx 

Hepatology

Accurate prediction of hepatocellular carcinoma risk in patients with chronic HBV infection: HBeAg status and HBsAg level matter.

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Letter to the editor: Considerations on the use of LPCN 1148 in cirrhotic patients with sarcopenia.

Pubmed   Journal   ReadQx 

Letter to the editor: Post-TIPS hemodynamic target adherence fails to improve outcomes in cirrhotic patients.

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Reply: Considerations on the use of LPCN 1148 in cirrhotic patients with sarcopenia.

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Reply: Post-TIPS hemodynamic target adherence fails to improve outcomes in cirrhotic patients.

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther

Editorial: 'Risk-Adapted Starting Ages of Colorectal Cancer Screening for People With Diabetes or Metabolic Syndrome'. Authors' Reply.

Pubmed   Journal   ReadQx 

Editorial: How to Interpret Clinical Impact of Viral Replication Activity for Postoperative Recurrence of HBV-Related HCC-Authors' Reply.

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Editorial: Obesity and Outcomes on Advanced Therapy in Ulcerative Colitis-The Fat of the Matter: Authors' Reply.

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Letter on "Association Between Viral Replication Activity and Postoperative Recurrence of HBV-Related Hepatocellular Carcinoma"-Authors' Reply.

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Letter on "Association Between Viral Replication Activity and Postoperative Recurrence of HBV-Related Hepatocellular Carcinoma".

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Letter: Association Between Viral Replication Activity and Postoperative Recurrence of HBV-Related Hepatocellular Carcinoma.

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Letter: Comparing the Efficacy of Adjuvant PD-1 Inhibitor After Curative Resection for Metabolic Dysfunction-Associated Steatotic Liver Disease Related HCC Versus Other Aetiologies-Authors' Reply.

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Letter: Comparison of the Efficacy of Adjuvant PD-1 Inhibitor After Curative Resection for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Related HCC Versus Other Aetiologies.

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Letter: Inflammatory Potential of the Diet and Risk of Crohn's Disease and Ulcerative Colitis.

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Letter: Inflammatory Potential of the Diet and Risk of Crohn's Disease and Ulcerative Colitis. Authors' Reply.

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Letter: Lubiprostone Treatment for MASLD-Gender Imbalance and Blinding Considerations.

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Letter: Lubiprostone Treatment for MASLD-Gender Imbalance and Blinding Considerations. Authors' Reply.

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Letter: Meta-Analysis Critique: Refining the Association Between Helicobacter pylori and Eosinophilic Oesophagitis.

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Letter: Meta-Analysis Critique: Refining the Association Between Helicobacter pylori and Eosinophilic Oesophagitis. Authors' Reply.

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Gastroenterology

A large language model chatbot would only be as intelligent as the mind that uses it!

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Comments on "Use of Large Language Models to Identify Surveillance Colonoscopy Intervals-A Feasibility Study".

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Gastrointest Endosc

Challenges in managing poorly differentiated esophageal adenocarcinoma: insights from long-term study.

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Concerns regarding bleeding risk of cold snare resection for colorectal polyps in patients with antiplatelet agents.

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Consideration of the risk score model of lymph node metastasis in early gastric cancer based on EUS.

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Endoscopic management of Zenker's diverticulum: need for standardization for high-quality comparative data.

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Refining endoscopic resection criteria for early gastric cancer in elderly patients.

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Ultra-low-volume bowel preparation for colonoscopy: much more to explore.

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Gut

Germline mutations and pancreatic cancer risk in chronic pancreatitis.

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J Hepatol

MELD-Creatinine: The C®at is out of the bag.

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Rat Hepatitis E: A Silent Threat or Overestimated Risk?

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Thyroid Function and MASLD Risk Stratification in Children with Obesity: a not negligible link.

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J Neurogastroenterol Motil

Rapid Progression of Nonspecific Esophageal Motor Disorder to Type II Achalasia and Recovery of Peristalsis After Pneumatic Dilation.

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